Selank is a synthetic seven-amino-acid peptide derived from tuftsin, a naturally occurring tetrapeptide fragment of the immunoglobulin G heavy chain. It was developed in Russia and appears mostly in preclinical research. This guide covers the molecule, the research context, and how to verify a batch.
- Sequence
- Thr-Lys-Pro-Arg-Pro-Gly-Pro
- Structure
- Seven amino acids, approx. 752 Da; tuftsin (Thr-Lys-Pro-Arg) with a Pro-Gly-Pro extension
- Supplied as
- Lyophilised vials
- Purity method
- RP-HPLC; identity by mass spectrometry
- Regulatory status
- Not licensed as a medicine in the UK or EU
What Selank is
Tuftsin, the Thr-Lys-Pro-Arg fragment, is rapidly broken down in tissue. Selank adds a Pro-Gly-Pro tail to the tuftsin sequence, a design intended to make the molecule more resistant to enzymatic degradation. At seven residues it is short and straightforward to synthesise and characterise.
What the research literature studies
Published preclinical work examines how Selank relates to cytokine expression and to the enzymes that break down enkephalins, among other pathways, in cell and animal models. These are laboratory findings. Nothing on this page is a claim about effects in people.
Identity and purity: what a good CoA shows
Because the molecule is short, the mass-spectrometry result is decisive: the observed mass should be close to the theoretical figure of about 752 Da. RP-HPLC then shows whether other peptide fragments, such as truncated sequences, are present.
- RP-HPLC purity with the chromatogram attached
- Observed intact mass close to the theoretical value
- A batch reference that matches your vial label
Handling and storage
Proline-rich peptides like this one are generally stable as lyophilised powder when kept cold, dry and out of light. Once in solution, use the stability guidance in our reconstitution and shelf-life articles.
Regulatory status
Selank is not licensed as a medicine in the UK or EU. Material supplied by Nordapep is for in vitro laboratory research only and must not be used in people or animals.
Questions researchers ask
What is Selank derived from?
It is derived from tuftsin, a four-amino-acid fragment of the immunoglobulin G heavy chain, with a Pro-Gly-Pro tail added to make it more resistant to breakdown.
How big is the Selank molecule?
It is a heptapeptide (seven amino acids) of roughly 752 Da, so mass spectrometry gives a clear identity check.
Is Selank a licensed medicine in the UK?
No. It is not licensed in the UK or EU. Nordapep supplies it for in vitro laboratory research only.
